Methods for synthesizing α4β7 peptide antagonists
US10407468B2 · kind B2 · utility
11Cited by
18References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 23, 2017 |
| Grant date | Sep 10, 2019 |
| Priority date | — |
| Expiry date | Mar 23, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods of making α4β7 peptide monomer and dimer antagonists. Methods of the present invention include solid phase and solution phase methods, as well as synthesis via condensation of smaller peptide fragments. Methods of the present invention further include methods directed to the synthesis of peptides comprising one or more penicillamine residues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.