Mosaic chimeric viral vaccine particle
US10407491B2 · kind B2 · utility
3Cited by
1References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 28, 2017 |
| Grant date | Sep 10, 2019 |
| Priority date | — |
| Expiry date | Sep 28, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/855
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes compositions and methods for priming protective immunity in the presence of pre-existing maternal antibody. In some embodiments, the invention contemplates simultaneously masking vaccines to avoid antibody neutralization while targeting those vaccines to specific cell types in order to elicit an enhanced immune response. In other embodiments, vectors that recruit and activate specific antigen-presenting cells may further enhance the efficacy of those immune responses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.