Use of microvesicles in analyzing nucleic acid profiles

US10407728B2 · kind B2 · utility

Assignee

• The General Hospital Corporation · US

Inventors

• Mikkel Noerholm · Martinsried, DE
• Johan Karl Olov Skog · Boston, US
• Xandra O. Breakefield · Newton, US
• Bob Carter · San Diego, US

Key dates

• Filing date: Jul 6, 2015
• Grant date: Sep 10, 2019
• Expiry date: Jul 6, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention concerns gene signatures obtained from microvesicles and a method of applying these gene signatures in helping to determine a biological condition. The determination of a biological condition may aid, for example, the diagnosis, prognosis, and therapy treatment selection for disease in a subject.