Method of preparing ezetimibe and intermediate thereof
US10414736B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Sep 28, 2018 |
| Grant date | Sep 17, 2019 |
| Priority date | — |
| Expiry date | Sep 28, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed is a method of preparing ezetimibe, including cross-metathesis using a Grubbs 2nd catalyst and deprotection using a Pearlman's catalyst, and an intermediate thereof. The method of preparing ezetimibe is useful as an efficient ezetimibe synthesis technique in pharmaceutical fields using ezetimibe as a raw material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.