Patent · US Active

Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

US10414752B2 · kind B2 · utility

16Cited by

8References

20Claims

0Family size

Assignee

FORMA Therapeutics, Inc. · US

Inventors

Jian Lin · Watertown, US
Anna Ericsson · Keyano, CA
Ann-Marie Campbell · Monroe, US
Gary Gustafson · Ridgefield, US
Zhongguo Wang · Lexington, US
R. Bruce Diebold · Waltham, US
Susan Ashwell · Plainsboro, US
David R. Lancia, Jr. · Boston, US
Justin Andrew Caravella · Cambridge, US
Wei Lu · Newton, US

Key dates

Filing date	Apr 27, 2018
Grant date	Sep 17, 2019
Priority date	—
Expiry date	Apr 27, 2038

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/47
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The application relates to an inhibitor of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula (I-13):

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.