Compounds and methods for modulating TMPRSS6 expression
US10415038B2 · kind B2 · utility
4Cited by
28References
29Claims
0Family size
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Key dates
| Filing date | Apr 4, 2016 |
| Grant date | Sep 17, 2019 |
| Priority date | — |
| Expiry date | May 26, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3527
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are compositions and compounds comprising modified oligonucleotides for modulating TMPRSS6 and modulating an iron accumulation disease, disorder and/or condition in an individual in need thereof. Iron accumulation diseases in an individual such as polycythemia, hemochromatosis or β-thalassemia can be treated, ameliorated, delayed or prevented with the administration of antisense compounds targeted to TMPRSS6.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.