L-menthol dosage forms having a proteinaceous coating for enhanced storage stability
US10420730B2 · kind B2 · utility
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37References
33Claims
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Key dates
| Filing date | Oct 6, 2015 |
| Grant date | Sep 24, 2019 |
| Priority date | — |
| Expiry date | Oct 6, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A storage stable L-menthol composition including a tablet, caplet, capsule, or sachet dosage form has therein a core containing crystalline L-menthol and at least one pharmaceutical excipient. A proteinaceous coating of a continuous film of proteinaceous material is over the core. The film is effective to substantially prevent the crystalline L-menthol from volatilizing and leaving the core when stored at a temperature of 40 degrees C. and 75% relative humidity from between 1 day to 30 days. The dosage form contains an effective amount of the crystalline L-menthol for treating a gastrointestinal disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.