Patent · US Active

Variants of IgG Fc with limited amine groups

US10421796B2 · kind B2 · utility

0Cited by
1References
7Claims
0Family size

Inventor

Key dates

Filing dateJan 21, 2015
Grant dateSep 24, 2019
Priority date—
Expiry dateMar 27, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Lysine-depleted variants of fragment crystallizable (Fc) regions of immunoglobulins are disclosed. Also disclosed are fusion proteins comprised of N-terminal targeting or active peptide domains fused with such lysine-depleted variant IgG-Fc domains. Polynucleotides encoding such proteins, compositions and kits containing such proteins, and methods of using such proteins are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.