Chimeric antigen receptors and methods of use
US10421810B2 · kind B2 · utility
2Cited by
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19Claims
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Assignee
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Key dates
| Filing date | Oct 7, 2016 |
| Grant date | Sep 24, 2019 |
| Priority date | — |
| Expiry date | Oct 7, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Chimeric antigen receptors containing tumor necrosis factor receptor superfamily member transmembrane domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.