Preparation method of near-infrared silver sulfide quantum dots
US10421901B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 1, 2015 |
| Grant date | Sep 24, 2019 |
| Priority date | — |
| Expiry date | May 6, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0013
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a preparation method of near-infrared silver sulfide quantum dots. The silver sulfide quantum dots have hydrophilic groups derived from a mercapto-containing hydrophilic reagent attached on the surface thereof, and the hydrophilic reagent is any one of mercaptoacetic acid, mercaptopropionic acid, cysteine, cysteamine, thioctic acid and ammonium mercaptoacetate or any combination thereof. The silver sulfide quantum dots have high fluorescence yield, good fluorescence stability, good biocompatibility and uniform sizes. The preparation method has moderate reaction conditions, simple operation, short production cycle, good reproducibility and is easy to control. The silver sulfide quantum dots can be used in the application of cellular imaging and biological tissue imaging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.