Patent · US Active

Mutant organophosphorus acid anhydrolase enzymes having increased catalytic efficiency on V-agents

US10421952B1 · kind B1 · utility

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21Claims

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Assignee

The United States of America as represented by the Secretary of the Army · US

Inventors

Steven P. Harvey · Timonium, US
Mark A. Guelta · White Marsh, US

Key dates

Filing date	Jan 30, 2018
Grant date	Sep 24, 2019
Priority date	—
Expiry date	Mar 16, 2038

Classification

Technology area (CPC A)Human Necessities
CPC primaryA62D2101/26
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention is directed toward mutant, non-wild-type organophosphorus acid anhydrolases (OPPAs) having three or more site mutations, methods of production, kits and methods of use to effectively degrade toxic V-agent type chemical compounds such as VX, VR, CVX, and VM.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.