Patent · US Active

Profiling peptides and methods for sensitivity profiling

US10422788B2 · kind B2 · utility

11Cited by

85References

19Claims

0Family size

Assignee

TOLERO PHARMACEUTICALS, INC. · US

Inventors

David J. Bearss · Alpine, US
Adam Siddiqui-Jain · South Jordan, US
Clifford J. Whatcott · Lehi, US
Peter W. Peterson · Salt Lake City, US
Steven L. Warner · Sandy, US
Lars Mouritsen · Lehi, US

Key dates

Filing date	Feb 19, 2019
Grant date	Sep 24, 2019
Priority date	—
Expiry date	Feb 19, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/56
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure is generally directed to profiling peptides, compositions, and kits, as well as methods of use thereof. The profiling peptides comprise an Mcl-1 binding domain, and optionally a cellular uptake moiety. The methods of using such profiling peptides include predicting sensitivity of a cancer, selecting a treatment, treating a cancer, producing a sensitivity profile, and the like.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.