Triple reuptake inhibitors and methods of their use
US10428021B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Nov 20, 2017 |
| Grant date | Oct 1, 2019 |
| Priority date | — |
| Expiry date | Nov 20, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are bicyclic compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders. Compounds provided herein inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations containing the compounds are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.