Compositions and methods using capsids resistant to hydrolases
US10428329B2 · kind B2 · utility
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Key dates
| Filing date | Oct 17, 2017 |
| Grant date | Oct 1, 2019 |
| Priority date | — |
| Expiry date | Oct 17, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/18142
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel processes and compositions are described which use viral capsid proteins resistant to hydrolases to prepare virus-like particles to enclose and subsequently isolate and purify target cargo molecules of interest including nucleic acids such as siRNAs and shRNAs, miRNAs, messenger RNAs, small peptides and bioactive molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.