Patent · US Active

Non-natural amino acid replication-dependent microorganisms and vaccines

US10428333B2 · kind B2 · utility

1Cited by

132References

11Claims

0Family size

Assignee

Ambrx, Inc. · US

Inventors

Feng Tian · San Diego, US
Brad Hehli · San Diego, US

Key dates

Filing date	Aug 9, 2013
Grant date	Oct 1, 2019
Priority date	—
Expiry date	Aug 9, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N9/93
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compositions and methods of producing vaccines, including methods wherein whole organism vaccines are provided with limited replication abilities, thereby increasing vaccine safety and efficacy, through the use of non-natural, unnatural, or non-naturally encoded amino acids.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.