Biocatalytic production of l-fucose

US10428361B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Vaidotas Navickas · Mannheim, DE
• Michael Breuer · Darmstadt, DE
• Michael Puhl · Hirschberg, DE
• Melanie WEINGARTEN · Ludwigshafen am Rhein, DE
• Kai-Uwe Baldenius · Ludwigshafen, DE
• Wolfgang Siegel · Schifferstadt, DE

Key dates

• Filing date: Feb 19, 2016
• Grant date: Oct 1, 2019
• Expiry date: Feb 19, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y111/01007
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to biocatalytic methods, comprising purely enzymatic, mixed enzymatic-fermentative and purely fermentative methods, for the direct single-step conversion of L-fucitol to L-fucose, in order to easily obtain L-fucose at high amounts and levels of purity. Suitable recombinant microorganisms and fungi are further disclosed and also the use thereof in said method for the single-step conversion to L-fucose.