Multifocal method and apparatus for stabilization of optical systems
US10429628B2 · kind B2 · utility
4Cited by
2References
35Claims
0Family size
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Key dates
| Filing date | Apr 22, 2016 |
| Grant date | Oct 1, 2019 |
| Priority date | — |
| Expiry date | Apr 22, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30204
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and apparatus for deep microscopic super resolution imaging use two independent and variable focal planes. Movements of fiducial markers imaged using one focal plane are monitored and used to provide real-time or near real-time correction for sample drift. A second focal plane may be used to collect light for super-resolution imaging of a sample. A prototype embodiment has produced low drift when imaging many microns deeper than the fiducial markers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.