Patent · US Active

Compositions and methods for organ preservation

US10433538B2 · kind B2 · utility

2Cited by

15References

12Claims

0Family size

Assignee

University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

Paulo Artur Chaves Fontes · Pittsburgh, US
William R. Light · Natick, US

Key dates

Filing date	Oct 11, 2013
Grant date	Oct 8, 2019
Priority date	—
Expiry date	Feb 10, 2035

Classification

Technology area (CPC A)Human Necessities
CPC primaryA01N1/143
WIPO fieldBasic materials chemistry
WIPO sectorChemistry

Abstract

Disclosed herein are solutions for use with machine perfusion of one or more organs. In some embodiments, the solutions comprise acellular cross-linked hemoglobin in a physiologically acceptable medium. Also disclosed herein are methods for machine perfusion of one or more organs, for example utilizing the disclosed perfusion solutions. In some embodiments, the methods include perfusing an organ with an oxygenated solution (such as the disclosed solutions) which is at a temperature between about 12-37° C., for example at a temperature of about 21° C.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.