Single-cell label-free photoacoustic flowoxigraphy in vivo
US10433733B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 6, 2016 |
| Grant date | Oct 8, 2019 |
| Priority date | — |
| Expiry date | Jul 8, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2291/02872
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for obtaining a 3-D OR-PAM image of microvasculature within a region of interest of a subject is provided. The method includes: focusing a first light pulse at a first depth beneath a first surface position within the region of interest; receiving a first PA signal in response to the first light pulse; focusing a second light pulse at a second depth beneath the first surface position within the region of interest; receiving a second PA signal in response to the second light pulse; and forming the 3-D OR-PAM image by combining the first PA signal and the second PA signal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.