Medicament for the treatment of viral skin and tumour diseases

US10434059B2 · kind B2 · utility

Assignee

• Fougera Pharmaceuticals Inc. · US

Inventors

• Yunik Chang · Toms River, US
• Robert Lathrop · Novato, US
• Erwin Bohm · Ladenburg, DE
• Irene Gander-Meisterernst · Stockdorf, DE
• Regina Greger · Iffeldorf, DE
• Johanna Holldack · Aarhus, DK
• Ulrich Moebius · Gauting, DE

Key dates

• Filing date: Aug 18, 2017
• Grant date: Oct 8, 2019
• Expiry date: Aug 18, 2037

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a medicament containing a compound of general formula (I), where R1=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C11-C21 alkyl, alkylene or alkinyl group, preferably a C11-C15 alkyl, alkylene or alkinyl group, particularly a C11-C13 alkyl, alkylene or alkinyl group, most preferably a C13 alkyl group, R2=independently, a straight or branched C1-C8 alkyl, alkylene or alkinyl group, preferably a C1-C6 alkyl, alkylene or alkinyl group, in particular a C2-C4 alkyl, alkylene or alkinyl group, most preferably a C3 alkyl group, a —[CH2—(CH2)m-O]nH group with n=1 to 10, preferably n=1 to 5, to m=1 to 5, preferably m=1 to 3, a —CH2—[CH—(OH)]p[CH2—R3]— group, where R3=independently H or OH, p=1 to 7, preferably p=1 to 4, a pentose group or a hexose group, as therapeutically active agent, alone or in combination with one or several further pharmaceutical agents as a combination preparation for the treatment of viral skin diseases and/or tumor diseases, in particular caused by human papilloma virus (HPV) and/or herpes viruses and a topically acting medicament formulation and the use thereof.