Para-xylene films and therapeutic uses thereof
US10434225B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 29, 2016 |
| Grant date | Oct 8, 2019 |
| Priority date | — |
| Expiry date | Mar 29, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides single sheet and compound para-xylene films for therapeutic uses. For example, the present invention provides single sheet para-xylene films useful as tissue separators and/or adhesion barriers in a subject, where the top and/or bottom surfaces of such films have a water contact angle between 75 and 95 degrees (e.g., to prevent adhesion formation). The present invention also provides compound films composed of at least two para-xylene polymer films with a therapeutic molecule layer in between. Such compound films, when used in vivo (e.g., as a tissue separator and to treat inflammation or atrial fibrillation) allow either therapeutic molecule elution through one of the para-xylene layers, or therapeutic molecule release when the compound film is pierced, such as when it is sutured in place.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.