Patent · US Active

6,7-cyclicmorphinan derivatives and use thereof

US10435406B2 · kind B2 · utility

0Cited by

25References

24Claims

0Family size

Assignee

PURDUE PHARMA L.P. · US

Inventors

Andrew J. Kassick · Wexford, US
Dawit Tadesse · Avenel, US
Laykea Tafesse · Robinsville, US

Key dates

Filing date	Dec 3, 2015
Grant date	Oct 8, 2019
Priority date	—
Expiry date	Dec 3, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/05
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The application provides compounds of Formula I and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, dash line a, dash line b, W, Z, X, and m are defined as set forth in the specification. The invention is also directed to use of the compounds of Formula I and the pharmaceutically acceptable salts and solvates thereof to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. In certain embodiments, the Compounds of the Invention are useful for treating pain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.