Patent · US Active

Chemically-locked bispecific antibodies

US10435479B2 · kind B2 · utility

0Cited by

1References

9Claims

0Family size

Assignee

SORRENTO THERAPEUTICS, INC. · US

Inventors

Yanwen Fu · San Diego, US
Gunnar F. Kaufmann · San Diego, US
Bryan Edward Jones · Carmel, US
Raheleh Toughiri · San Diego, US

Key dates

Filing date	May 10, 2015
Grant date	Oct 8, 2019
Priority date	—
Expiry date	May 11, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

There is disclosed a process for forming chemically-locked bispecific or heterodimer antibodies, preferably in the IgG class, in high specificity and with high homogeneity. More specifically, there is disclosed a chemically-locked bispecific IgG class antibody having a linkage region joined together with bio-orthogonal click chemistry.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.