Method of co-expressing a glycoprotein and a single-subunit olicosaccharyltransferase in a plant

US10435704B2 · kind B2 · utility

Assignee

• Icon Genetics GmbH · DE

Inventors

• Franziska Jarczowski · Röblingen am See, DE
• Romy Kandzia · Bodenwerder, DE
• Frank Thieme · Halle (Saale), DE
• Victor Klimyuk · Leipzig, DE
• Yuri Gleba · Berlin, DE

Key dates

• Filing date: Jun 3, 2014
• Grant date: Oct 8, 2019
• Expiry date: Jun 3, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/41
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A process of producing a recombinant glycoprotein in a plant, in cells of a plant, or in plant cells is provided. The process comprises expressing in said plant, in cells of said plant or in said plant cells a nucleic acid sequence encoding a polypeptide having an N-glycosylation site and co-expressing a nucleic acid sequence encoding a heterologous single-subunit oligosaccharyltransferase.