Mitigating meniscus effects in vertically oriented circular dichroism spectrometery
US10436644B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Oct 6, 2016 |
| Grant date | Oct 8, 2019 |
| Priority date | — |
| Expiry date | Oct 6, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/216
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Example embodiments of methods, apparatus, and systems for measuring polarimetric parameters using spectroscopy are disclosed herein. Particular embodiments concern circular dichroism (CD) spectrometers that use a vertically aligned beam. In such embodiments, the solution being analyzed may have a top surface that forms a convex or concave meniscus, creating a surface through which the measuring beam passes that may refract the beam in undesirable ways. Accordingly, particular embodiments of the disclosed technology include one or more meniscus-compensating (meniscus-effect-reducing) components or subsystems. These components and/or subsystems can be used alone or in combination with one another to reduce the undesirable refractive effects caused by the meniscus at the solution's surface, thereby improving the resulting quality of the spectroscopy measurement and potentially improving the speed with which CD spectroscopy can be performed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.