Patent · US Active

Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease

US10442798B2 · kind B2 · utility

2Cited by
61References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 7, 2018
Grant dateOct 15, 2019
Priority date
Expiry dateFeb 7, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D513/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention provides tetrahydroquinoline sulfonamide compounds, tetrahydronaphthalene sulfonyl compounds, and related compounds, pharmaceutical compositions, methods of promoting RORy activity, methods of increasing the amount of IL-17 in a subject, and methods of treating cancer and other medical disorders using such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.