Patent · US Active

Compositions and methods for TCR reprogramming using fusion proteins

US10442849B2 · kind B2 · utility

17Cited by

55References

27Claims

0Family size

Assignee

TCR2 THERAPEUTICS INC. · US

Inventors

Patrick Baeuerle · Gauting, DE
Gregory Sieczkiewicz · Wellesley, US
Robert Hofmeister · Scituate, US

Key dates

Filing date	Jan 30, 2017
Grant date	Oct 15, 2019
Priority date	—
Expiry date	Jan 30, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2510/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are T-cell receptor (TCR) fusion proteins (TFPs), T-cells engineered to express one or more TFPs, and methods of use thereof for the treatment of diseases, including cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.