Serum albumin-binding fibronectin type III domains
US10442851B2 · kind B2 · utility
3Cited by
46References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 19, 2015 |
| Grant date | Oct 15, 2019 |
| Priority date | — |
| Expiry date | May 17, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to polypeptides which include tenth fibronectin type III domains (10Fn3) that binds to serum albumin, with south pole loop substitutions. The invention further relates to fusion molecules comprising a serum albumin-binding 10Fn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.