Fermentation process for producing itaconic acid under nitrogen free conditions
US10443077B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Feb 16, 2016 |
| Grant date | Oct 15, 2019 |
| Priority date | — |
| Expiry date | Feb 16, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y401/01006
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for the production of itaconic acid, which method comprises fermenting a recombinant cell capable of producing itaconic acid in a suitable fermentation medium, thereby to produce itaconic acid, wherein: (a) the recombinant cell: (i) overexpresses cis-aconitate decarboxylase; and (ii) overexpresses a part of the citric acid cycle and/or has reduced activity of a native metabolic route to acetate and/or lactate; and, optionally, (b) the fermentation is carried out under anaerobic conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.