Patent · US Active

Recurrent SPOP mutations in prostate cancer

US10443102B2 · kind B2 · utility

0Cited by

2References

21Claims

0Family size

Assignee

Cornell University · IT

Inventors

Mark A. Rubin · New York, US
Christopher Barbieri · New York, US

Key dates

Filing date	Feb 9, 2012
Grant date	Oct 15, 2019
Priority date	—
Expiry date	Apr 20, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates generally to new prostate cancer markers, and particularly to a class of cancer marked by the presence of missense mutations in SPOP, an E3 ubiquitin ligase component. The invention provides methods and materials for detecting and diagnosing prostate cancer by detecting these mutations and may be useful in predicting disease progression and response to therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.