Patent · US Active

Trapping mammalian protein-protein complexes in virus-like particles utilizing HIV-1 GAG-bait fusion proteins

US10444245B2 · kind B2 · utility

1Cited by

2References

11Claims

0Family size

Assignees

VIB VZW · BE
UNIVERSITEIT GENT · BE

Inventors

Jan Tavernier · Balegem, BE
Sven Eyckerman · Nazareth, BE

Key dates

Filing date	May 24, 2013
Grant date	Oct 15, 2019
Priority date	—
Expiry date	Jan 26, 2034

Classification

Technology area (CPC G)Physics
CPC primaryG01N2570/00
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The disclosure relates to a virus-like particle in which a protein complex is entrapped, ensuring the formation of the protein complex under physiological conditions, while protecting the protein complex during purification and identification. The disclosure further relates to the use of such virus-like particle for the isolation and identification of protein complexes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.