Pharmaceutical formulation of palbociclib and a preparation method thereof
US10449195B2 · kind B2 · utility
1Cited by
6References
8Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 5, 2017 |
| Grant date | Oct 22, 2019 |
| Priority date | — |
| Expiry date | Jun 5, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular weight material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.