Chemokine CXCR4 and CCR5 receptor modulators and uses related thereto

US10450293B2 · kind B2 · utility

Assignee

• EMORY UNIVERSITY · US

Inventors

• Bryan D. Cox · Atlanta, US
• Lawrence Wilson · Mason, US
• Anthony Prosser · Atlanta, US
• Dennis C. Liotta · Atlanta, US
• James P. Snyder · Atlanta, US

Key dates

• Filing date: May 15, 2015
• Grant date: Oct 22, 2019
• Expiry date: May 15, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure relates to chemokine receptor modulators and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein or pharmaceutically acceptable salts or prodrugs thereof. In certain embodiments, the compositions disclosed herein are used for managing chemokine related conditions, typically prevention or treatment of viral infections such as HIV or for managing cancer.