Carbonic anhydrase IX (G250) antibodies and methods of use thereof
US10450383B2 · kind B2 · utility
1Cited by
21References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 9, 2017 |
| Grant date | Oct 22, 2019 |
| Priority date | — |
| Expiry date | Sep 29, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are the methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.