Single nucleotide polymorphisms (SNP) and association with resistance to immune tolerance induction
US10450610B2 · kind B2 · utility
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Key dates
| Filing date | Jun 15, 2016 |
| Grant date | Oct 22, 2019 |
| Priority date | — |
| Expiry date | Jul 10, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This application discloses methods, systems and kits for correlating the presence or absence of certain nucleic acid sequences within a population with the ability to create immune tolerance in that same population. Tolerance can be induced by solo or repeated administration of antigen, including soluble antigens administered either intravenously or sublingually. This application also discloses methods for detecting variants. In addition the application addresses the use or avoidance of non steroidal anti inflammatory drugs in therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.