Compositions and methods related to engineered erythoid cells comprising 4-1BBL

US10456421B2 · kind B2 · utility

Assignee

• Rubius Therapeutics, Inc. · US

Inventors

• Avak Kahvejian · Lexington, US
• Jordi Mata-Fink · Baltimore, US
• Robert J. Deans · Riverside, US
• Tiffany F. Chen · Cambridge, US
• John Round · Cambridge, US
• Noubar B. Afeyan · Lexington, US
• Torben Straight Nissen · Sharon, US
• Nathan Dowden · Winchester, US
• Tom Wickham · Groton, US
• Sivan Elloul · Newton, US

Key dates

• Filing date: Sep 26, 2017
• Grant date: Oct 29, 2019
• Expiry date: Sep 26, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2510/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.