Patent · US Active

Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof

US10457703B2 · kind B2 · utility

8Cited by
4References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 30, 2016
Grant dateOct 29, 2019
Priority date
Expiry dateMar 30, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J51/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds represented by Formula I, or pharmaceutically acceptable salts, stereoisomers, solvates, hydrates or combination thereof, The invention also provides pharmaceutical compositions comprising these compounds and methods of using this compounds for treating FXR-mediated or TGR5-mediated diseases or conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.