Patent · US Active

Compositions and methods for treating cancer

US10457729B2 · kind B2 · utility

2Cited by

26References

30Claims

0Family size

Assignees

The Trustees of the University of Pennsylvania · US
Fondazione IRCCS Istituto Nazionale Dei Tumori · IT

Inventors

Daniel J. Powell, Jr. · Bala-Cynwyd, US
George Coukos · Lansdowne, US
Mariangela Figini · Milano, IT
Silvana Canevari · Segrate, IT

Key dates

Filing date	Jul 18, 2016
Grant date	Oct 29, 2019
Priority date	—
Expiry date	Feb 19, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/74
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having α-folate receptor (FRα) binding domain and 4-1BB (CD137) costimulatory domain to treat ovarian cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.