Co-delivery of cholesterol lowering drugs and nutraceuticals
US10457759B2 · kind B2 · utility
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Key dates
| Filing date | Jul 20, 2017 |
| Grant date | Oct 29, 2019 |
| Priority date | — |
| Expiry date | Sep 29, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08F2500/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Star polymer occlusion complexes were prepared comprising i) an amphiphilic unimolecular star polymer having a crosslinked core covalently linked to 6 or more independent amphiphilic polymer arms, ii) a nutraceutical (such as coenzyme Q10), and iii) a cholesterol-lowering drug (such as simvastatin). An initial occlusion complex formed with the nutraceutical and the star polymer exhibited improved binding properties for the cholesterol-lowering drug, resulting in improved loading efficiencies for the cholesterol-lowering drug. The star polymer occlusion complexes have utility in the medical treatment of high blood cholesterol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.