Corneal epithelioid cells derived from surface ectodermal cells
US10457913B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Jan 12, 2016 |
| Grant date | Oct 29, 2019 |
| Priority date | — |
| Expiry date | Jan 13, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/15043
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for inducing a keratin 12-positive corneal epithelioid cell from a surface ectoderm-derived cell. More specifically, the present invention relates to a method for inducing a keratin 12-positive corneal epithelioid cell, comprising introducing PAX6, KLF4, and OCT4 into a surface ectoderm-derived cell, such as an oral mucosal epithelial cell, and a corneal epithelioid cell induced by the method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.