Patent · US Active

Protein arrays and methods of using and making the same

US10457935B2 · kind B2 · utility

5Cited by
196References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 10, 2011
Grant dateOct 29, 2019
Priority date—
Expiry dateMay 27, 2034

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01J2219/00725
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Methods and devices are provided for preparing a protein array having a plurality of proteins. In one embodiment, the method includes providing a plurality of nucleic acids each having a predefined sequence and expressing in vitro a plurality of proteins from the plurality of nucleic acids. In another embodiment, protein arrays having a solid surface and a microvolume are also provided. The solid surface can have a plurality of anchor oligonucleotides capable of hybridizing with a plurality of nucleic acids. The microvolume can cover each of the plurality of anchor oligonucleotides and can be configured to produce a polypeptide from each of the plurality of nucleic acids.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.