Biomarker RNF6 for colorectal cancer
US10457993B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Mar 30, 2016 |
| Grant date | Oct 29, 2019 |
| Priority date | — |
| Expiry date | Oct 1, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/54
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method for diagnosing of colorectal cancer in a subject and a method for determining risk of recurrence of colorectal cancer among colorectal cancer patients by detecting overexpression of the RNF6 gene, which in some cases is due to a higher than normal copy number of the genomic sequence of this gene. A kit and device useful for such methods are also provided. In addition, the present invention provides a method for treating colon cancer by suppressing RNF6 gene expression or activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.