Optical trap for rheological characterization of biological materials

US10459212B2 · kind B2 · utility

Assignee

• The United States of America as Represented by the Secretary, Dept. of Health and Human Services · US

Inventors

• Kandice Tanner · Rockville, US
• Benjamin H. Blehm · Tucson, US
• Alexus Devine · Bethesda, US

Key dates

• Filing date: Jul 29, 2016
• Grant date: Oct 29, 2019
• Expiry date: Nov 5, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2203/0094
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Systems and methods for assaying the viscoelastic properties of a heterogeneous material are provided. The systems and methods allow for application of an in situ calibrated optical trap to optical trap beads within the material to assay the viscoelastic properties. In several embodiments, the material can be a biological material, such as tumor tissue or skin tissue.