Determination of tissue oxygenation in vivo
US10463286B2 · kind B2 · utility
4Cited by
79References
21Claims
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Key dates
| Filing date | Feb 10, 2017 |
| Grant date | Nov 5, 2019 |
| Priority date | — |
| Expiry date | Jan 22, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2562/043
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A system and method for noninvasively determining the oxygenation of a tissue, for example, a muscle, in vivo uses optical methods to optically interrogate the tissue in both a visible wavelength range and a near infrared (NIR) wavelength range. The illuminating light is sculpted in intensity to approximately match the absorbance spectrum, for example, with the visible light having an intensity an order of magnitude greater than the NIR light. Training data is obtained from healthy patients in both the visible and NIR ranges simultaneously and used to calculate muscle oxygenation.
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