Injectable delivery of microparticles and compositions therefor
US10463619B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 3, 2015 |
| Grant date | Nov 5, 2019 |
| Priority date | — |
| Expiry date | Dec 3, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2400/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods of making and using of microparticle compositions that provide faster flow or improved injectability through smaller or small-diameter needles have been developed. Notably, the microparticle compositions can be successfully delivered or administered through smaller-diameter needles than other microparticle compositions prepared from biocompatible or biodegradable polymers including, for example, poly(lactide), poly(lactide-co-glycolide), polycaprolactone, or poly-3-hydroxybutyrate. The microparticle compositions can exhibit a higher solids loading for a given needle size and/or faster flow through needles than other microparticle compositions. Further, blending or mixing the polymer of the microparticle composition with other polymer formulations can enhance the injectability of the resulting formulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.