Thromboresistant-anticoagulant extracellular matrix
US10463769B2 · kind B2 · utility
1Cited by
6References
20Claims
0Family size
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Key dates
| Filing date | Dec 18, 2015 |
| Grant date | Nov 5, 2019 |
| Priority date | — |
| Expiry date | Dec 18, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/42
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Provided herein are bioactivated polymer/extracellular matrix (ECM) composites and methods of preparation and use thereof. In particular, heparinized cysteine-polymer/ECM composites, and methods of preparation and use thereof, are provided. In some embodiments, provided herein are compositions comprising a composite of: (a) extracellular matrix (ECM), and (b) a polyester covalently linked to a bioactive agent. In some embodiments, the composite is a homogeneous composite. In some embodiments, the ECM is decellularized ECM. In some embodiments, the ECM is not substantially crosslinked.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.