Patent · US Active

In vitro transcription methods and constructs

US10465190B1 · kind B1 · utility

73Cited by

16References

14Claims

0Family size

Assignee

ModernaTX, Inc. · US

Inventors

Jesse Chen · Lake Forest, US
Athanasios Dousis · Pasadena, US

Key dates

Filing date	Dec 21, 2016
Grant date	Nov 5, 2019
Priority date	—
Expiry date	Mar 21, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2840/60
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present disclosure provides, in some aspects, in vitro transcription systems (including, for example, nucleic acid constructs and polymerases), the use of which increases transcription efficiency while reducing the amount of truncated single-stranded ribonucleic acid transcript produced during an in vitro transcription reaction.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.