Stable proteins and methods for designing same
US10468119B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Sep 8, 2016 |
| Grant date | Nov 5, 2019 |
| Priority date | — |
| Expiry date | May 22, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16C20/60
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A method for designing and selecting a protein having a stabilized structure compared to a corresponding wild type protein, and proteins having at least six amino acid substitutions with respect to a corresponding wild type protein, designed for improved thermal stability, improved specific activity and/or improved expression levels, are provided herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.