Patent · US Active

Management of ischemia using pooled mesenchymal stromal cell composition

US10471101B2 · kind B2 · utility

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16Claims
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Assignee

Inventors

Key dates

Filing dateMar 25, 2015
Grant dateNov 12, 2019
Priority date
Expiry dateMar 25, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2502/1394
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure relates to composition comprising pooled and expanded allogeneic mesenchymal Stromal cells (MSCs) and a method for management of Ischemia using the composition thereof. In particular, the disclosure relates to bone marrow derived pooled and expanded allogeneic MSC compositions with effective dosage ranges and modes/route of administration for effective management of Ischemia. The disclosure also relates to the use of conditioned medium rich in bioactive factors in combination with the cell composition for managing ischemic conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.