Patent · US Active

Spirocyclic indolone polyethylene glycol carbonate compound, composition, preparation method and use thereof

US10471154B2 · kind B2 · utility

0Cited by

0References

11Claims

0Family size

Assignee

Fei Xiao · CN

Inventors

Jie Ma · Nanjing, CN
Fei Xiao · 安丰镇, CN
Hongjun Ren · Beijing, CN
Wei Wang · Hsinchu, TW
Hongtao Xu · Tianjin, CN
Meng Wang · Taichung, TW
Lihui Zou · Beijing, CN
Fei Ding · Thalwil, CH
Fei Su · Shanghai, CN

Key dates

Filing date	Aug 8, 2016
Grant date	Nov 12, 2019
Priority date	—
Expiry date	Aug 8, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a spirocyclic indolone polyethylene glycol carbonate compound, a composition thereof, a preparation method therefor, and a use thereof as an anticancer drug due to the antitumor activity thereof. The structural formula of the spirocyclic indolone polyethylene glycol carbonate compound is shown below. The compound has excellent tumor inhibitory activity, water solubility, low toxicity, and can be used for intravenous injection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.